Wow this is fascinating. I’ll read about it more :)

So once the cell under immune response makes the antibody, the antibody is a big complex organic molecule right? Have there been any success with synthesizing it in vitro with some crazy ass chemical synthesis? Or cloning such with engineered cells? You said it’s possible with immortal cancer cells. After all cells do not generate antibody out of thin air, the cloning ‘algorithm’ should be somewhere coded.

Why the antibodies can’t be analyzed and chemically synthesized in lab? I’m a total noob in immunology but haven’t we got quite good at synthesizing organic stuff with say custom bacteria?